Introduction
In the race to modernize data centers, organizations are looking for infrastructure solutions that provide flexibility, performance, and operational efficiency. The convergence of compute, storage, and networking is no longer a trend, but a new foundation for IT strategy. Integrating Nutanix hyperconverged infrastructure (HCI) with Dell PowerFlex software-defined storage gives enterprises a powerful combination that is ready for today’s demanding workloads and tomorrow’s innovation.
This article explores the architectural synergy, technical benefits, and practical best practices for bringing Nutanix and Dell PowerFlex together in your data center.
Why Convergence Is Reshaping Data Centers
Traditional IT architectures often relied on siloed, hardware-defined systems. As digital transformation accelerates, organizations need environments that can scale quickly, reduce complexity, and deliver consistent performance across multiple workloads. Converged and hyperconverged platforms have emerged as the answer—bringing compute, storage, and networking into a unified, software-driven ecosystem.
By combining Nutanix’s robust HCI management with the elasticity of Dell PowerFlex’s software-defined storage, enterprises can:
- Streamline operations and reduce management overhead
- Improve scalability and resource utilization
- Achieve better resilience and faster time to value
The Unique Value of Nutanix + Dell PowerFlex
When you integrate Nutanix with Dell PowerFlex, you leverage best-in-class HCI and next-gen storage for a solution that’s greater than the sum of its parts. Here’s why this partnership matters:
- Agility: Rapidly deploy infrastructure for any workload, from VDI to databases
- Performance: High throughput and low latency, even at scale
- Operational Simplicity: Centralized management, automation, and streamlined updates
Let’s break down the key capabilities of each platform before exploring how they work together.
What is Nutanix?
Nutanix is a leader in hyperconverged infrastructure, delivering a software-centric platform that integrates compute, storage, networking, and virtualization. Built to run on commodity hardware, Nutanix transforms on-premises environments into cloud-like private clouds.
Key Capabilities
- Hyperconverged Infrastructure (HCI): Combines compute, storage, and networking into a single, software-defined solution
- Management & Automation: Intuitive Prism interface for simplified operations, policy-based automation, and one-click upgrades
- Resilience & Security: Built-in data protection, snapshots, disaster recovery, and security compliance
- Flexible Deployment: Support for multiple hypervisors (AHV, ESXi, Hyper-V) and hardware platforms
What is Dell PowerFlex?
Dell PowerFlex is a next-generation, software-defined storage platform. It disaggregates compute and storage, allowing for independent scaling and dynamic allocation of resources.
Next-Gen Software-Defined Storage Overview
- Flexibility: Decouples storage from compute, supporting a variety of deployment models (HCI, two-layer, storage-only)
- Only the two-layer (disaggregated) model is supported in the Nutanix + PowerFlex integration.
- Linear Scalability: Add nodes to scale capacity and performance independently
- Performance: High IOPS and low latency for mission-critical workloads
- Enterprise-Grade Resilience: Built-in data protection, fault tolerance, and automated healing
- Multi-Platform Support: Compatible with VMware, Red Hat, Microsoft, and more
Integration Architecture
High-Level Design
Below is a conceptual diagram of the integrated architecture:

- Compute: Nutanix clusters handle compute workloads and provide virtualization
- Storage: Dell PowerFlex provides shared, scalable storage
- Networking: High-speed Ethernet links, typically 25/40/100Gb, connect compute and storage
Key Integration Points
- Storage Integration: Nutanix nodes access Dell PowerFlex storage via block protocols (iSCSI or NVMe/TCP), presenting PowerFlex volumes as datastores for VMs or containers
- Management: Separate management planes for Nutanix Prism and PowerFlex Manager, with optional REST API integration
- Networking: Dedicated VLANs or network segments isolate storage traffic from production workloads, ensuring optimal throughput and security
Benefits of Integration
Performance
- Dell PowerFlex’s parallel data path architecture eliminates bottlenecks, delivering consistent, high-performance storage to Nutanix nodes
- Supports latency-sensitive applications (e.g., databases, analytics)
Scalability
- Independently scale compute (Nutanix) or storage (PowerFlex) based on workload requirements
- Start small and expand non-disruptively as business needs grow
Flexibility
- Support for multiple hypervisors, bare metal, and container environments
- Easily adapt to hybrid or multi-cloud deployments
Operational Simplicity
- Centralized management with Nutanix Prism and PowerFlex Manager
- There is no native unified management. REST APIs can be used for integration, but it requires custom development or orchestration tools.
- Automated provisioning, monitoring, and lifecycle management
Deployment Scenarios
Private Cloud:
Run business-critical applications and databases on a private cloud foundation with Nutanix compute and PowerFlex storage. Easily support mixed workloads and tiered storage needs.
VDI (Virtual Desktop Infrastructure):
Enable high-density, high-performance virtual desktops, with rapid provisioning and consistent user experience.
Analytics & Big Data:
Leverage PowerFlex’s high IOPS for real-time analytics and large-scale data ingestion, while Nutanix provides compute resources and management.
Hybrid Cloud:
Bridge on-premises and cloud environments, using Nutanix’s hybrid cloud features and PowerFlex’s scalable storage to burst or migrate workloads as needed.
Best Practices
Sizing
- Right-size compute and storage resources based on workload characteristics and future growth
- Use sizing tools from Nutanix and Dell to model requirements
Compatibility
- Ensure firmware and driver compatibility between Nutanix hardware and PowerFlex storage nodes
- Validate supported OS, hypervisor, and PowerFlex software versions
Network & Topology Tips
- Use dedicated 25Gb+ Ethernet links for storage traffic
- Separate management, storage, and data networks using VLANs
- Design for redundancy (dual fabric, multiple uplinks) to maximize availability
Getting Started
Prerequisites
- Validated hardware for both Nutanix and Dell PowerFlex nodes
- Compatible hypervisor and OS versions
- High-speed networking (10Gb minimum, 25Gb+ recommended)
- Access to both Nutanix Prism and PowerFlex Manager
High-Level Steps
- Plan & Size: Assess workloads and plan resource allocation
- Deploy PowerFlex Storage: Set up PowerFlex cluster and configure storage pools
- Deploy Nutanix Cluster: Install Nutanix software and hypervisor of choice
- Integrate Storage: Connect Nutanix nodes to PowerFlex storage via iSCSI/NVMe
- Validate & Test: Run performance and compatibility tests
- Go Live: Move workloads, monitor, and optimize
Resources
Conclusion
The combination of Nutanix and Dell PowerFlex creates a unified, modern platform for the future-ready data center. IT architects and sysadmins can achieve exceptional agility, performance, and simplicity by integrating these industry-leading solutions. Whether building private clouds, VDI farms, or analytics clusters, this partnership unlocks the flexibility and scale demanded by today’s business landscape.
Ready to modernize your data center?
Explore a pilot or proof-of-concept, or dive deeper into the documentation to see how unified hyperconverged power can transform your IT strategy.
Disclaimer: The views expressed in this article are those of the author and do not represent the opinions of Dell, Nutanix, or any affiliated organization. Always refer to the official Dell and Nutanix documentation before production deployment.